Be part of revolutionizing immune-mediated medicine

Precision. Reimagined. Together.

Our work is discovering and developing precision therapies for immune-mediated diseases. Personalized medical treatments are a game changer, designed to drastically improve health outcomes. This mission motivates our individual growth, our team potential, and our high-performance results.

If you have a passion for improving the lives of patients and want to help us build a first-ever precision immunology company—we want to hear from you.

See current job listings
Prometheus Biosciences headquarters.

Awards and recognition

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Certified as a Great Place to Work
Prometheus Biosciences is certified as great place to work.
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Named one of BioSpace’s best places to work in 2022 and 2023
Prometheus Biosciences was named one of BioSpace's best places to work in 2022 and 2023.
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Awarded Best Places to Work by San Diego Business Journal
Prometheus Biosciences was awarded Best Places to Work by San Diego Business Journal.

What our employees say


Motto: Precision, Reimagined, Together
Title: Prometheus Biosciences

Team member 1

So, I think we’re on a great journey, but the journey is all around.

Improving the lives of our patients is what this company is aiming to do.

Precision, a more personalized approach is what this company is about.

Team member 2

Being a part of this company means a ride of a lifetime and the opportunity of a lifetime.

Team member 3

I really came to realize over the years that I’d like to do science that translates.

I’d like to do science that’s not just a science fair project.

When you work in the lab for a while, at some point I want to get into the clinic.

So, what it means for me to be at Prometheus is to have a direct connection with what works in patients.

Team member 4

Because we’re making a difference for patients, this is simply game-changing.

Team member 6

This platform that we’ve been fortunate to be given, provides us with a treasure trove of information.

We can pioneer precision medicine and immunology.

Team member 7

Good hires lead to good hires.

Over just a few short years, it has been an experience of a lifetime.

Team member 8

Science, the technology, the premise, is absolutely fascinating.

Team member 9

Being part of this company, for me, it’s about growth and opportunity.

You know, I’m thrilled to be in an environment where we can build this company together.

Team member 10

The only company so far that I’ve been part of that has very clear focus.

Team member 11

What this company means is reducing suffering in people’s everyday lives.

Team member 12

Means the opportunity to bring personalized medicine to patients in need.

Team member 13

All of my science that’s been done is going to go out.

Team member 4

I’m most excited about our ability to change the course of IBD therapy.

Team member 1

I think we’re truly going to deliver things that are going to change people’s lives.

The opportunity of starting with a genetic signature, all the way through to developing a drug, and then using that genetic signature to get that drug to the right patient.

Team member 3

About taking precision medicines into autoimmunity, which hasn’t been done before.

Team member 4

And I think that’s really what gets me out of bed every day and keeps me focused.

Team member 2

You have a drug that have a unique mechanism of action.

You have a platform that is probably the best shot at precision medicine at this time.

Team member 14

Event is a marking of time. It’s a celebration of the one-year mark since the company went public.

It’s the celebration of everything that’s been done since the founding of the company.

It’ll be really exciting to see the fruit of the labor and the hard work that we’ve done actually play out.

Team member 8

Well, I think it’s an absolute game-changer.

Team member 13

The coming together of so many talented people.

They’re gonna drive this way beyond.

It includes everyone in the company.

Team member 3

And what we’re trying to have people realize today is that we do have a long-term plan.

Team member 14

That is really what I’m learning.

Knowing, getting to know people, their ideas and how they think.

It’s been great.

Team member 6

The opportunity to work with new colleagues.

Team member 10

The leadership team is really asking everyone for their voice.

That means that everyone can affect the future of the company, which is great.

Team member 6

Building trust, learning from one another.

Team member 6 presenting to crowd

I can’t do it without you.

We’re in this together.

Thank you all very much for coming.


Advance your career in the bioscience hub of San Diego

Our headquarters are nestled near the Pacific Ocean in Torrey Pines, San Diego’s high-tech innovation hub. San Diego is a place where you will never run out of things to do. It has highly rated schools, great restaurants, and outdoor activities to enjoy. Our offices and lab are state-of-the-art. We know that a professional work environment can put us in the right frame of mind to do our best work.

Get to know us and our values

The Prometheus Biosciences culture drives us to create innovative and transformative solutions. We are early adopters of new tools and fresh ideas. We welcome inter-disciplinary input and critical thinking. And we always base our decisions on the science and data.

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We let passion fuel progress

  • Focus on the patient through precision
  • Relentlessly work to fulfill our mission
  • Show compassion
  • Give space to create
  • Trust others to do their jobs
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We follow the science and data

  • Follow the highest scientific standards
  • Identify and eliminate bias
  • Design studies with scientific goals
  • Make data driven decisions
  • Engage in rigorous, honest debate
  • Embrace constructively, challenging each other without impeding relationships
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We evolve continuously

  • Be accountable to each other
  • Ask for feedback
  • Model behaviors for coworkers
  • Demonstrate humility by being open to other ideas
  • Intentionally learn/unlearn/relearn
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We embrace moonshot thinking

  • Be bold: no guts, no glory
  • Take calculated risks
  • Speak up
  • Raise hand to accept challenges
  • Embrace audacious thinking
  • Collaborate
  • Expand beyond what is possible

Giving back to the community

At Prometheus Biosciences, we believe that contributing our time and resources to charities is our responsibility. Prometheus Biosciences leadership and team members are encouraged to volunteer with non-profit organizations to make a difference in the community. Opportunities to volunteer include working with local and national non-profits.

Here are two foundations that Prometheus Biosciences actively supports:

Crohn's & Colitics Foundation logo.

The Crohn’s & Colitis Foundation is a non-profit, volunteer-driven organization dedicated to finding the cures for Crohn’s disease and ulcerative colitis.

Live Sciences Cares San Diego logo.

Life Science Cares activates the financial and human capital of the life sciences industry to disrupt the cycle of poverty and inequality in our communities.

Note for staffing agencies and search firms

Prometheus Biosciences does not accept unsolicited resumes from agencies. If you choose to submit candidates without prior Human Resources approval, you do so with the understanding that if those candidates are hired, Prometheus Biosciences will not pay any fee.